Neuroprotective effect of panax notoginseng saponins and its main components
نویسندگان
چکیده
منابع مشابه
Neuroprotective effect of panax notoginseng saponins and its main components
Stroke is the third leading cause of death and the first cause of adult disability in industrial countries [1]. It is charicaterized by hemiplegia, hemianopsia, aphasia, mouth askew and sever sequelae. It is considered that an ischemic disease without any specific treatment method and few effective drugs such as tPA (human tissue-type plasminogen activator) and Edarovone with specific therapeut...
متن کاملDetermination of Panax notoginseng Saponins
The feasible, reliable and selective multi-template molecularly imprinted polymers (MT17 MIPs) based on SBA-15 (SBA-15@MT-MIPs) for the selective separation and determination of the 18 trace level of ginsenoside Rb1 (Rb1), ginsenoside Rg1 (Rg1) and notoginsenoside R1 (R1) (Panax 19 notoginseng saponins, PNS) from biological samples were developed. The polymers were 20 constructed by SBA-15 as s...
متن کاملNeuroprotective Properties of Panax notoginseng Saponins via Preventing Oxidative Stress Injury in SAMP8 Mice
Inhibiting oxidative damage in early stage of Alzheimer's disease (AD) is considered as a strategy for AD treatment. Our previous study has shown that Panax notoginseng saponins (PNS) have an antiaging action by increasing the levels of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-PX) in the serum of aged rats. In this study, we aimed to investigate the effects of...
متن کامل[Anti-inflammatory effects of total saponins of Panax notoginseng].
AIM To study the anti-inflammatory effects of total saponins of Panax notoginseng (PnS). METHODS Rat air-pouch acute inflammatory model was established with s.c. carrageenan (Car, 25 mg.kg-1). The protein content in exudate was measured. Micro-acid titration assay and radioimmunoassay (RIA) were applied respectively to investigate effects of PnS on phospholipase A2 (PLA2) activity and dinopro...
متن کاملPharmacokinetics study of bio-adhesive tablet of Panax notoginseng saponins
Panax notoginseng saponin (PNS) is the main active gradient of Chinese traditional medicine Panax notoginseng. Although its prominent therapeutic efficacy has been demonstrated by various researchers, the broader application is restricted by the low bioavailability of PNS. This article aims to discuss PNS's plasma pharmacokinetics after oral administration of bio-adhesive tablet of PNS to beagl...
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ژورنال
عنوان ژورنال: World Journal of Neuroscience
سال: 2014
ISSN: 2162-2000,2162-2019
DOI: 10.4236/wjns.2014.41002